For the purpose of integrating cytogenetic, radiation hybrid, linkage and sequence maps of the human genome, as well as for research on cancer, a number of clones have been selected for and mapped by Fluorescent in-situ Hybridization at a 1Mb resolution. This set of clones, which mostly contains clones from our human library (RPCI-11) and clones from the Caltech Human Libraries is also known as the HBRC_1 set (Human BAC Resource Consortium_1 set).

This project has been carried out through a collaboration of several different groups and coordinated by Barbara J.Trask (Integration of cytogenetic landmarks into the draft sequence of the human genome, The BAC Resource consortium, Nature 409, 953-958 (2001)). Funding for the project was provided by the National Cancer Institute. Our Resources & Research Section provides more information on the project, which brought about the construction of these resources.

A complete and updated list is available from the National Center for Biotechnology Information's website. About a third (3967) of these clones are currently distributed by CHORI BACPAC Resources.

Clones from this collection can be ordered individually through our online ordering system by requesting the particular clone while specifying in the "comment section" of the requisition: "PLEASE PROVIDE THE FISH-CONFIRMED VERSION OF THIS CLONE". The clones are also available by ordering the entire collection (in deepwell blocks) or by ordering the entire collections specific for particular chromosomes. Such orders cannot be placed online and require an email communication with [email protected]. The entire collection is contained in forty-six 96 deepwell blocks, which have been arranged according to chromosome order. Clones from duplicated regions (hybridizing to mutiple chromosomes) are called "multisite clones" and these clones have been arrayed into separate blocks.

Due to regular updates of the complete list, and the possibility of future reorganization of the collection in the blocks, a release number - currently 1.3 - was assigned to it. Please consult the Resources and Research section of our site (http://bacpacresources.org/mapped-clones.htm) to see the content of these collections.

The collection is also subject to an ongoing quality control effort in our facilities ensuring the quality and reliability of our FISH Mapped Clone resource. Please contact our BACPAC manager for more details related to the quality assessment.

Pricing includes labor, reagents, reasonable part of the equipment usage, maintenance costs and institutional overhead charges. Plates can only be ordered by subsets of chromosome (2 to 3 plates).

For ordering and shipping details, please view the ordering and pricing information page.